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* If you have chronic moderate acne the dose for the first month should be increased to the 12 tablet/day regimen for the first month. Then the dose can be reduced to 8 tablets a day during the second month. For those individuals over 185 pounds with chronic moderate acne an initial 2-4 weeks of 18 tablets/day may be necessary.
** For individuals with chronic severe acne an initial dose of 18 tablets/day for 2-4 weeks may be necessary. Once noticeable improvement is achieved the dose may be reduced to 12 tablets daily. For individuals with chronic severe acne and weighing over 185 pounds the 18 tablet/day dose may be needed for 2 months.
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