|Product||All Natural Botanical Ingredients||Skin Irritation, Sensitivity Or Rush||Restricted Sun Exposure||Safe for Stomach||Safe for Pregnancy||Prevents New Acne From Re-Occurring|
|Tetracycline &other Antibiotics (Systemic)||NO||YES||YES||NO||NO||NO|
|Benzoyl Peroxide (BP) (Topical)||NO||YES||YES||Topical||Warning||NO|
|Differin (Adapalene) (Topical)||NO||YES||YES||Topical||Warning Category C2||NO|
|Azelex (Topical)||NO||YES||YES||Topical||Warning Category B2||NO|
|Salicylic Acid (Topical)||NO||YES||YES||Topical||Warning||NO|
|Accutane1 (Lsotretinoin) (Systemic)||NO||YES||YES||NO||NO||Class Action|
|Proactiv (BP & Salicylate) (Topical)||NO||YES||YES||Topical||Warning||NO|
Information derived from the 2010 Physicians Desk Reference. Revised by Herborium Group, Inc., 2011.
1 Accutane has been reported to cause severe depression especially in young men
2 Products in categories C and B relating to pregnancy should only be used after consulting your physician
|Category A||"Controlled studies in women fail to demonstrate a risk to the fetus in the first trimester (and there is no evidence of a risk in later trimester), and the possibility of fetal harm appears remote."||For all practical purposes, there are no Category A drugs.|
|Category B||"Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the first trimester (and there is no evidence of a risk in later trimesters)."||Category B drugs include prenatal vitamins, acetaminophen and several other medications used routinely and safely during pregnancy. If there is a clinical need for a Category B drug, it is considered safe to use it.|
|Category C||"Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus."||Category C drugs have not been shown to be harmful to fetuses (if they had been, they wouldn't be Category C drugs). However, there are some reasons to be more concerned about these drugs than Category B drugs. If the pregnant patient will benefit from a Category C drug, it is generally used, although most obstetricians would prefer a Category B drug if it will give equivalently good results.|
|Category D||"There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective.)"||Category D drugs have some significant risks. They should be used during pregnancy only when the alternatives are worse.|
|Category X||"Studies in animals or humans have demonstrated fetal abnormalities or there is evidence of fetal risk based on human experience or both, and the risk of the use of the drug in pregnant women clearly outweighs any possible benefit. The drug is contraindicated for those who are or may become pregnant."||Category X drugs should not be used during pregnancy|
The FDA has implemented tighter controls designed to ensure that women do not take isotretinoin, Roche AG's drug to treat severe acne, during pregnancy. The US regulator said the changes would help prevent many of the miscarriages and birth defects associated with the drug.
Benzoyl peroxide can cause premature skin aging, slow healing, and is associated with increased skin cancer risks. In 1995, the FDA issued warnings regarding the use of benzoyl peroxide and changed its status from "safe" to "uncertain." Salicylic acid may dry the skin, causing irritation and redness. AcnEase doesn't dry or irritate skin, regardless of skin tone and type.
Some customers comment that AcnEase is more expensive than over-the-counter treatments like Clearasil and others. The extremely high quality of our unique herbal ingredients, means you may have to pay a bit more. But you can't put a price on safety, and if you've tried multiple acne solutions over a period of years, you've probably already spent thousands.